Directly use conductive materials in tissue engineering applications

Article type: Research Article

Authors: Feng, Ke^{a; b; 1; *} | Wei, Wenbo^{b; c; 1} | Yang, Chen^a | Dong, Shaozheng^a

Affiliations: [a] Dalian University of Science and Technology, Dalian, Liaoning, China | [b] Jiangxi University of Science and Technology, Ganzhou, Jiangxi, China | [c] Shenzhen Institute of Geriatrics, Shenzhen, China

Correspondence: [*] Corresponding author: Ke Feng. E-mail: kingfisher3721@126.com.

Note: [1] F. K. and W. W. contributed equally to this work.

Abstract: Artificial scaffolds play an important role in tissue engineering, which is used to mimic extracellular matrix (ECM) and provide a suitable microenvironment for cell growth. Many natural and synthetic biomaterials have been used to fabricate two dimensional or three dimensional scaffolds. However, missing electrical conductivity of these materials is one of the disadvantages. Recently, conductive polymers (CPs) and conductive nanomaterials (CNMs) have been chosen for doping into scaffolds to improve their conductivity. This review focuses on conductive scaffolds design, fabrication and application in tissue engineering for enhancing cell attachment and proliferation, promoting differentiation and maturation with and without electrical stimulations.

DOI: 10.3233/JCB-190018

Journal: Journal of Cellular Biotechnology, vol. 6, no. 1, pp. 23-46, 2020