Affiliations:
Department of Neurology, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China
Correspondence:
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Correspondence to: Jingping Shi, Department of Neurology, The Affiliated Brain Hospital of Nanjing Medical University, P.O. Box 210029, No. 264 Guangzhou Road, Nanjing, China. E-mail: profshijp@163.com.
Abstract: The thyroid gland is crucial for the regulation of metabolism, growth, and development of various tissues, organs, systems, including the central nervous system. Recent studies have implicated the role of thyroid dysfunction in the etiology of Alzheimer’s disease (AD), while AD leads to a significant increase in the prevalence of thyroid dysfunction. In this review, we have analyzed the role of thyroid function in the pathophysiology of AD as well as its biomarkers. The present review aims to provide encouraging targets for early screening of AD risk factors and intervention strategies.
