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Article type: Review Article
Authors: Szablewski, Leszek; *
Affiliations: Medical University of Warsaw, Department of General Biology and Parasitology, Warsaw, Poland
Correspondence: [*] Correspondence to: Leszek Szablewski, Medical University of Warsaw, Chair and Department of General Biology and Parasitology, 5 Chalubinskiego Str, 02-004 Warsaw, Poland. Tel.: +48 22 621 26 07; Fax: +48 22 628 53 50; E-mail: leszek.szablewski@wum.edu.pl.
Abstract: Gut microbiota plays a crucial role in human health and disease. The alterations in the composition of gut microbiota may cause the onset of certain human pathologies. One of these is Alzheimer’s disease (AD). High-fat diets, administration of antibiotics, lack of probiotics and/or prebiotics in diet increase the risk of AD. On the other hand, modulation of the composition of gut microbiota may decrease the risk of AD and be able to slow down the progression of AD.
Keywords: Alzheimer’s disease, dysbiosis, gut microbiota, metabolic endotoxemia, physiology
DOI: 10.3233/JAD-170908
Journal: Journal of Alzheimer's Disease, vol. 62, no. 2, pp. 549-560, 2018
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