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Article type: Research Article
Authors: Lebowitz, Brian K.a; b; * | Weinstein, Cherylb | Beiser, Alexac; d; e | Seshadri, Sudhac; d; e | Wolf, Philip A.c; d; e | Auerbach, Sandfordc; d; e | Au, Rhodac; d; e
Affiliations: [a] Department of Neurology, Stony Brook University Medical Center, Stony Brook, NY, USA | [b] Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA | [c] Department of Neurology, Boston, University School of Medicine, Framingham Heart Study, Boston, MA, USA | [d] The National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, MA, USA | [e] Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
Correspondence: [*] Correspondence to: Brian K. Lebowitz, PhD, 14 Technology Drive, Suite 12B, East Setauket, NY 11733, USA. Tel.: +1 631 444 8053; Fax: +1 631 444 1975; E-mail: Brian.Lebowitz@stonybrookmedicine.edu.
Abstract: Although neuropsychological tests are commonly used in the evaluation of possible mild cognitive impairment (MCI), poor test scores may be indicative of factors other than neurological compromise. The current study assessed the role of lifelong reading disorder on MCI classification. Community dwelling older adults with a suspected developmental reading disorder were identified by inference based on reading test performance. Individuals with a suspected reading disorder were significantly more likely to perform at a level consistent with MCI on several commonly used neuropsychological tests. The findings suggest a relationship between a history of reading disorder and MCI classification.
Keywords: Alzheimer’s disease, cognition, dyslexia, learning disorders, memory disorders, mild cognitive impairment, neuropsychological tests
DOI: 10.3233/JAD-150543
Journal: Journal of Alzheimer's Disease, vol. 50, no. 1, pp. 41-45, 2016
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