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Article type: Short Communication
Authors: Raizes, Meytala; 1; * | Elkana, Odeliaa; 1; * | Franko, Mottya | Ravona Springer, Ramitb; c | Segev, Shlomod | Beeri, Michal Schnaidere; f
Affiliations: [a] Behavioral Sciences, Academic College of Tel Aviv-Yaffo, Israel | [b] Department of Psychiatry, Sheba Medical Center, Israel | [c] Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel | [d] Institute of Medical Screening, Sheba Medical Center Tel Hashomer, Israel | [e] Joseph Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Israel | [f] The Icahn School of Medicine at Mount Sinai, Department of Psychiatry, New York, NY, USA
Correspondence: [*] Correspondence to: Meytal Raizes, Academic College of Tel Aviv-Yaffo, 14 Rabeinu Yerucham St. P.O. 8401, Yaffo, 68114, Israel. Tel.: +972 3 680 2525; Fax: +972 3 680 2526; E-mail: meytal.raizes@gmail.com.
Correspondence: [*] Correspondence to: Odelia Elkana, Academic College of Tel Aviv-Yaffo, 14 Rabeinu Yerucham St. P.O. 8401, Yaffo, 68114, Israel. Tel.: +972 3 680 2525; Fax: +972 3 680 2526; E-mail: odelia.elkana@gmail.com.
Note: [1] These authors contributed equally to this work.
Abstract: We explored the association of plasma glucose levels within the normal range with processing speed in high functioning young elderly, free of type 2 diabetes mellitus (T2DM). A sample of 41 participants (mean age = 64.7, SD = 10; glucose 94.5 mg/dL, SD = 9.3), were examined with a computerized cognitive battery. Hierarchical linear regression analysis showed that higher plasma glucose levels, albeit within the normal range (<110 mg/dL), were associated with longer reaction times (p < 0.01). These findings suggest that even in the subclinical range and in the absence of T2DM, monitoring plasma glucose levels may have an impact on cognitive function.
Keywords: Plasma glucose level, cognitive function, processing speed, type 2 diabetes
DOI: 10.3233/JAD-150433
Journal: Journal of Alzheimer's Disease, vol. 49, no. 3, pp. 589-592, 2016
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