Affiliations: Department of Urology, Peking Union Medical College Hospital, CAMS &PUMC, Beijing 100730, China
Correspondence:
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Corresponding author: Zhi-Gang Ji, Department of Urology, Peking Union Medical College Hospital, CAMS &PUMC, No. 64 of Guangqumen Street, Dongcheng District, Beijing 100051, China. Tel.:/Fax: +86 10 6915 2510; E-mail:zhigangjidoc@163.com
Abstract: OBJECTIVE: This study aims to investigate the clinical value of
laparoscopic enucleation combined with selective arterial embolization for
the treatment of renal angiomyolipoma. METHODS: Data of patients
who underwent laparoscopic nephron-sparing surgery for renal angiomyolipoma
between July 2013 and November 2014 in our center were analyzed. RESULTS: Before surgery, 19 patients underwent selective arterial
embolization, while 24 patients did not receive this treatment.
Intraoperative blood loss was 46.4 ± 20.6 ml in the embolization group
and 89.5 ± 30.4 ml in the non-embolization group (P= 0.000). Operation
time was 90.3 ± 21.1 minutes in the embolization group and 131.7 ±
18.6 minutes in the non-embolization group (P= 0.000). Warm ischemia time was
9.5 ± 5.7 minutes in the embolization group and 24.2 ± 4.8 minutes
in the non-embolization group (P= 0.001). Hospitalization time was 7.7 ±
1.1 days in the embolization group and 6.3 ± 1.3 days in the
non-embolization group (P= 0.000). No serious complications occurred in
patients in the embolization group, while one patient developed urinary
leakage and another patient had angiomyolipoma in the operation area in the
non-embolization group. Three months after the operation, serum creatinine
level was 70.1 ± 13.7 μ mol/L in the embolization group and 84.2
± 9.1 μ mol/L in the non-embolization group (P= 0.000). No tumor
recurrence occurred in patients in both groups. CONCLUSION: Compared with laparoscopic partial nephrectomy alone, tumor enucleation
combined with selective arterial embolization can reduce blood loss and
shorten warm ischemia time.
