id	logFC	AveExpr	t	P.Value	adj.P.Val	B
KEGG_PEROXISOME	-0.410728510815508	-0.085177692207915	-18.277165945262	7.24426813897804e-58	1.318456801294e-55	120.925849873489
KEGG_DRUG_METABOLISM_CYTOCHROME_P450	-0.395942588447608	-0.186349329647024	-17.7896798598057	1.60483506847834e-55	1.46039991231529e-53	115.562656881453
KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM	-0.417414279888068	-0.197588701101045	-17.3163596367269	2.94115950222546e-53	1.78430343135011e-51	110.38801580372
KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS	-0.490719777103837	-0.184874105314045	-17.1699613475663	1.4634449629493e-52	6.65867458141931e-51	108.794686186629
KEGG_BUTANOATE_METABOLISM	-0.375257261571071	-0.163049885607773	-16.9442559054898	1.72442039581498e-51	6.27689024076652e-50	106.345358407557
KEGG_FATTY_ACID_METABOLISM	-0.420331016437538	-0.227296664390026	-16.5931843216293	7.85294848444401e-50	2.38206104028135e-48	102.553828694221
KEGG_STEROID_HORMONE_BIOSYNTHESIS	-0.349232248760826	-0.1140920454743	-16.4860415317852	2.50687945577972e-49	6.51788658502726e-48	101.401367722895
KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450	-0.360801123904691	-0.154483483380083	-16.210970825685	4.88379154142414e-48	1.11106257567399e-46	98.4531859055006
KEGG_RETINOL_METABOLISM	-0.380972944918956	-0.213576556827046	-16.1138295293023	1.38854932882654e-47	2.80795530940479e-46	97.4157976307642
KEGG_TRYPTOPHAN_METABOLISM	-0.384528180288672	-0.199093192456154	-16.0011708389018	4.65324240136606e-47	8.46890117048622e-46	96.2152434137226
KEGG_BETA_ALANINE_METABOLISM	-0.357309971434957	-0.185196874501557	-15.8766777195771	1.76486920243142e-46	2.92005631675016e-45	94.8918322966464
KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION	-0.414749856299677	-0.202828152574459	-15.4794146709838	1.21301861234963e-44	1.83974489539693e-43	90.6926669393838
KEGG_HISTIDINE_METABOLISM	-0.323172977401992	-0.153355803503482	-15.4688685512294	1.35648927170611e-44	1.89908498038856e-43	90.5817059644372
KEGG_DRUG_METABOLISM_OTHER_ENZYMES	-0.319079680802611	-0.111007273440709	-15.2226305483587	1.83047311997773e-43	2.37961505597105e-42	87.9988040996689
KEGG_TYROSINE_METABOLISM	-0.299812247648944	-0.170502311391061	-15.1605611954312	3.51874675392575e-43	4.26941272809658e-42	87.3501686047624
KEGG_PROPANOATE_METABOLISM	-0.386558053958202	-0.178818360392219	-14.7689508103683	2.12273500551421e-41	2.41461106877241e-40	83.2814395410539
KEGG_PPAR_SIGNALING_PATHWAY	-0.265426965768683	-0.111706282668873	-14.5660651548412	1.74632244730407e-40	1.86959226711377e-39	81.1902473061332
KEGG_LYSINE_DEGRADATION	-0.29042842825032	-0.0940565835006533	-13.4146974323452	2.15049253387545e-35	2.17438689536296e-34	69.5629642955081
KEGG_ASCORBATE_AND_ALDARATE_METABOLISM	-0.434579684357772	-0.129497355073348	-12.7989861193865	9.4228503759351e-33	9.02609878115889e-32	63.5321784552004
KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	-0.308096151051303	-0.188055502407695	-12.7680982436632	1.27374132159603e-32	1.15910460265239e-31	63.2334086368201
KEGG_ARGININE_AND_PROLINE_METABOLISM	-0.255597795422472	-0.143788962225056	-12.5587300888651	9.72957598526329e-32	8.14392373202815e-31	61.2181646298119
KEGG_LINOLEIC_ACID_METABOLISM	-0.273983235733673	-0.196222830453446	-12.5575177696913	9.84430341234171e-32	8.14392373202815e-31	61.2065465484767
KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS	0.215400576560324	0.0152879778920183	12.3289894312313	8.87727242227529e-31	7.02462426458305e-30	59.0271797836386
KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS	-0.365351447454462	-0.066056493401906	-12.3047227566352	1.11983475736873e-30	8.49208024337956e-30	58.797025712403
KEGG_PHENYLALANINE_METABOLISM	-0.29259989414191	-0.142790387349481	-11.9002532754277	5.18366061246389e-29	3.77370492587371e-28	54.9978062807148
KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION	0.251416168445384	0.0880726178095733	11.7318866928347	2.50524951780903e-28	1.75367466246632e-27	53.4374365128062
KEGG_PYRUVATE_METABOLISM	-0.264655485486003	-0.0718120309521428	-11.1410651695492	5.69402351697031e-26	3.83819362995776e-25	48.065401366515
KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM	-0.212345470664336	-0.128695325489615	-10.8060501275946	1.14671379405721e-24	7.45363966137185e-24	45.0943764407723
KEGG_CITRATE_CYCLE_TCA_CYCLE	-0.307040929028632	-0.0305139306838514	-10.7670523076309	1.62059956052477e-24	1.01706593108796e-23	44.7522090391035
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY	-0.156945104509272	-0.0792413080268435	-10.405001298464	3.87373305720946e-23	2.35006472137374e-22	41.6133119623497
KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM	-0.26466140420056	-0.107427164900152	-10.2246252576788	1.83539355797042e-22	1.07755363726005e-21	40.0755297162417
KEGG_FOLATE_BIOSYNTHESIS	-0.288749520920104	-0.138971109999701	-10.1453346054518	3.6166632499386e-22	2.05697722340258e-21	39.4051581650327
KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS	-0.264336533379733	-0.0577192707184096	-10.0998392292654	5.32918296676358e-22	2.93912515136658e-21	39.0220792002037
KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION	-0.192826080890706	-0.103416917249917	-10.0002680241659	1.23992585552972e-21	6.63725016783555e-21	38.1876931330165
KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM	-0.232567272340451	-0.0291794191858676	-9.6128630225893	3.14289008984357e-20	1.63430284671866e-19	34.9949087310308
KEGG_SELENOAMINO_ACID_METABOLISM	-0.214621199285946	-0.0451413191515319	-9.25642830904275	5.69889640919149e-19	2.88110874020237e-18	32.1350733105036
KEGG_CELL_CYCLE	0.190643025951905	0.132440137904973	9.10527168601784	1.90349361945116e-18	9.36313077675976e-18	30.9455007033055
KEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG	-0.215027008835049	-0.0618748670321388	-9.07252959031189	2.46723095888867e-18	1.18167377504668e-17	30.6896844318035
KEGG_PANCREATIC_CANCER	0.130565766875623	0.0103488464449038	8.91681863013256	8.39585411863199e-18	3.91806525536159e-17	29.4822632639919
KEGG_STARCH_AND_SUCROSE_METABOLISM	-0.194342218884978	-0.0936749018694647	-8.53085380990097	1.6367403295399e-16	7.26553024332345e-16	26.5559402319992
KEGG_NITROGEN_METABOLISM	-0.167725383333646	-0.133141473071143	-8.35251655713976	6.25168081630726e-16	2.70906168706648e-15	25.2366208740946
KEGG_LEISHMANIA_INFECTION	0.205699931798528	-0.0616313924666466	8.06823705136397	5.06972233099468e-15	2.13557926245207e-14	23.177609102957
KEGG_REGULATION_OF_ACTIN_CYTOSKELETON	0.102121172038925	0.00512801086967314	8.06572980624711	5.16293887625774e-15	2.13557926245207e-14	23.1596937647492
KEGG_O_GLYCAN_BIOSYNTHESIS	0.16490598687272	0.0182566115115286	7.93571499996758	1.32036600417293e-14	5.34014695021052e-14	22.2366149426859
KEGG_ABC_TRANSPORTERS	-0.157856220696448	-0.0634635420254741	-7.87050376730927	2.10549734158461e-14	8.33044600366086e-14	21.7780383271358
KEGG_BLADDER_CANCER	0.141822754417854	-0.00609428812082521	7.84146781046773	2.58931581225544e-14	1.00267122942658e-13	21.5748068480882
KEGG_OXIDATIVE_PHOSPHORYLATION	-0.199883838125998	0.0668786961674659	-7.81728348156112	3.0747786008588e-14	1.16585355282563e-13	21.4059838538107
KEGG_ARACHIDONIC_ACID_METABOLISM	-0.158068644593412	-0.151326359064933	-7.65801527152718	9.43866279824643e-14	3.50578903934868e-13	20.3044746841719
KEGG_GLYCEROLIPID_METABOLISM	-0.121987228705086	-0.0885206936719578	-7.65254310900196	9.80641783108993e-14	3.56953609051674e-13	20.2669481395368
KEGG_ALZHEIMERS_DISEASE	-0.137569809935082	0.0409824591620371	-7.52815763452178	2.32478664575559e-13	8.29629744171604e-13	19.4197169627263
KEGG_RIBOSOME	0.272717169599859	0.143959167966644	7.49006714475047	3.02159182447009e-13	1.05755713856453e-12	19.1624911168357
KEGG_SPLICEOSOME	0.180634194608848	0.174038819388965	7.42161950942454	4.8273233586204e-13	1.65768462503569e-12	18.7028975567975
KEGG_CYSTEINE_AND_METHIONINE_METABOLISM	-0.138602915780787	-0.0571784781466442	-7.36966156279461	6.87375720403718e-13	2.31671076136068e-12	18.3562949816435
KEGG_RENAL_CELL_CARCINOMA	0.113805575619196	0.0204658169695249	7.19931540391031	2.16035112720145e-12	7.14879827546661e-12	17.2338015151997
KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY	0.149179258428818	-0.00301411184134269	7.06934065680178	5.10347413414249e-12	1.65862909359631e-11	16.3917582141212
KEGG_GLYCOLYSIS_GLUCONEOGENESIS	-0.141276098412491	-0.0936557442270076	-7.00052112894334	8.00530007084142e-12	2.55607826823358e-11	15.9510163114104
KEGG_PARKINSONS_DISEASE	-0.180467414892851	0.0505313782729064	-6.92720632980156	1.28824471215672e-11	4.04242306228487e-11	15.4854033420879
KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS	-0.225589746479837	0.0706267813782701	-6.89401196220561	1.59581566913737e-11	4.92268562344071e-11	15.2759256836361
KEGG_GLUTATHIONE_METABOLISM	-0.155758395987317	-0.00294338488162795	-6.73300611562953	4.45607597381417e-11	1.32951774956423e-10	14.2717708620192
KEGG_CHRONIC_MYELOID_LEUKEMIA	0.107608646341797	0.0357455653167233	6.70434199938704	5.33909890966031e-11	1.54240635167965e-10	14.095079956746
KEGG_NOTCH_SIGNALING_PATHWAY	0.121363320206051	0.0339686218382195	6.37953027451842	3.96584851605121e-10	1.12778817175206e-09	12.1373942903612
KEGG_RENIN_ANGIOTENSIN_SYSTEM	-0.147763502951434	-0.0826851399670236	-6.33726893937616	5.11771308082397e-10	1.43295966263071e-09	11.888753662635
KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION	0.105096211261263	0.05149157469194	6.3320637504441	5.28048881922055e-10	1.45613479560324e-09	11.8582270534338
KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY	0.101007595431708	-0.0341504747412466	6.02862649309116	3.15951890037498e-09	8.45635940982716e-09	10.1159964652982
KEGG_SPHINGOLIPID_METABOLISM	0.102895096838514	0.0350711138298549	5.4502706152672	7.81730050684369e-08	2.00387139752895e-07	7.0027496965803
KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS	-0.14444127951151	0.0923894878218821	-5.44309958888408	8.12084804207818e-08	2.05276992174754e-07	6.96589089146867
KEGG_ALPHA_LINOLENIC_ACID_METABOLISM	-0.130343949991021	-0.0869470377399307	-5.34243904348742	1.38013470111328e-07	3.44088377537831e-07	6.45306991732202
KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE	0.141695571906753	-0.0285597834413988	5.30265461304936	1.69809414067986e-07	4.17639369734776e-07	6.25274576539266
KEGG_SULFUR_METABOLISM	-0.133137421411585	-0.157263004232719	-5.28238744287428	1.88631522775295e-07	4.55089763236865e-07	6.15121144230474
KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE	0.129584484925228	-0.0385860791586766	5.19896873677518	2.89719228609584e-07	6.76011533422362e-07	5.73697690960385
KEGG_ONE_CARBON_POOL_BY_FOLATE	-0.120447929984892	-0.0605717632011118	-4.93568645458061	1.08096360170264e-06	2.42883179641828e-06	4.46866756223586
KEGG_PANTOTHENATE_AND_COA_BIOSYNTHESIS	-0.113163420557293	-0.0502364170093562	-4.46940612585611	9.65643199956132e-06	2.0676124987296e-05	2.37038308902586
KEGG_HOMOLOGOUS_RECOMBINATION	0.112557505357058	0.104215539603235	4.31394747254345	1.9236488418856e-05	3.97845555935432e-05	1.71352530307832
KEGG_DNA_REPLICATION	0.134399388532504	0.20754009931886	4.22345071333635	2.84600571168893e-05	5.74946035101419e-05	1.3411085742191
KEGG_STEROID_BIOSYNTHESIS	-0.140855469686446	0.0994258578650486	-3.87810188129931	0.000118937245754926	0.000216465787273965	-0.0120927478127237
KEGG_TYPE_I_DIABETES_MELLITUS	0.102400417695712	-0.0710954013872068	3.22371378316351	0.00134576312297777	0.00216751228656596	-2.27576045845068
KEGG_GRAFT_VERSUS_HOST_DISEASE	0.115232548913082	-0.0890942906445492	3.17801006649452	0.00157213885896748	0.00250990589764983	-2.41894705818771