Affiliations: Klinik und Poliklinik für Urologie,
Universitätsklinikum Carl Gustav Carus, Fetscherstraße 74, 01307
Dresden. E-mail: oliver.hakenberg@uniklinikumdresden.de
Abstract: Renal transplantation is the oldest established organ
transplantation technique and internationally the most widely used
transplantation treatment. Renal transplantation not only replaces the
insufficient renal excretory function and enables independence from chronic
dialysis treatment but also reestablishes all other renal functions. Successful
renal transplantation thus leads to a remarkable improvement in general health
and quality of life. The lack of suitable donor organs has led to an increase
in the numbers of living donor renal transplantations; however, for the
majority of recipients cadaveric donation remains the standard treatment.
Therapeutic immunosuppression remains a lifelong necessity for transplant
recipients and this leads to inevitable problems with side-effects and patient
compliance.
Keywords: Renal transplantation, immunosuppression, organ procurement, live donor transplantation