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An induction heating device using planar coil with high amplitude alternating magnetic fields for magnetic hyperthermia

Issue title: Papers from the 3rd International Conference on Biomedical Engineering and Technology (iCBEB 2014), 25–28 September 2014, Beijing, China

Subtitle:

Guest editors: Edward J. Ciaccio

Article type: Research Article

Authors: Wu, Zuhe | Zhuo, Zihang | Cai, Dongyang | Wu, Jian'an | Wang, Jie | Tang, Jintian*

Affiliations: Key Laboratory of Particle Technology and Radiation Imaging, Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing, China

Correspondence: [*] Corresponding author: Jintian Tang, Key Laboratory of Particle Technology and Radiation Imaging, Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing, China. Tel.: +86 010 62796769; Fax: +86 010 62789237; E-mail:tangjt@mail.tsinghua.edu.cn

Keywords: Magnetic hyperthermia, magnetic nanoparticles, planar coil, power abortion, induction heating

DOI: 10.3233/THC-150955

Journal: Technology and Health Care, vol. 23, no. s2, pp. S203-S209, 2015

Published: 2015
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Abstract

BACKGROUND: Induction heating devices using the induction coil and magnetic nanoparticles (MNPs) are the way that the magnetic hyperthermia is heading.

OBJECTIVE: To facilitate the induction heating of in vivo magnetic nanoparticles in hyperthermia experiments on large animals.

METHODS: An induction heating device using a planar coil was designed with a magnetic field frequency of 328 kHz. The coil's magnetic field distribution and the device's induction heating performance on different concentrations of magnetic nanoparticles were measured.

RESULTS: The alternating magnetic field produced in the axis position 165 mm away from the coil center is 40 Gs in amplitude; magnetic nanoparticles with a concentration higher than 80 mg. mL-1 can be heated up rapidly.

CONCLUSION: Our results demonstrate that the device can be applied not only to in vitro and in small animal experiments of magnetic hyperthermia using MNPs, but also in large animal experiments.

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