Affiliations: [a] Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, China | [b] School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Tianjin, China | [c] Department of Obstetrics and Gynecology, Affiliated Hospital of Weifang Medical University, Weifang, Shandong, China
Correspondence:
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Corresponding authors: Yinuo Fan and Hui Yu, Academy of Medical Engineering and Translational Medicine, Tianjin University, No. 92 Weijin Road, Tianjin 300072, China. E-mail: xiaonuomi@tju.edu.cnandyuhui@tju.edu.cn.
Note: [1] These authors contributed equally to this work.
Abstract: BACKGROUND: Colposcopy is one of the common methods of cervical cancer screening. The type of cervical transformation zone is considered one of the important factors for grading colposcopic findings and choosing treatment. OBJECTIVE: This study aims to develop a deep learning-based method for automatic classification of cervical transformation zone from colposcopy images. METHODS: We proposed a multiscale feature fusion classification network to classify cervical transformation zone, which can extract features from images and fuse them at multiple scales. Cervical regions were first detected from original colposcopy images and then fed into our multiscale feature fusion classification network. RESULTS: The results on the test dataset showed that, compared with the state-of-the-art image classification models, the proposed classification network had the highest classification accuracy, reaching 88.49%, and the sensitivity to type 1, type 2 and type 3 were 90.12%, 85.95% and 89.45%, respectively, higher than the comparison methods. CONCLUSIONS: The proposed method can automatically classify cervical transformation zone in colposcopy images, and can be used as an auxiliary tool in cervical cancer screening.
Keywords: Cervical cancer, deep learning, colposcopy, image processing, feature fusion
