Comparison of evaluation parameters in the retinal layer between diabetic cystoid macular edema and postoperative cystoid macular edema after cataract surgery based on a hierarchical approach
Issue title: Recent Innovations on Biomedical Engineering
Affiliations: [a] Department of Medical Biotechnology, Dongguk University-Bio Medi Campus, Seoul, Korea | [b] Department of Medical Devices Industry, Dongguk University-Seoul, Seoul, Korea
Correspondence:
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Corresponding author: Sung Min Kim, Department of Medical Biotechnology, Dongguk University-Bio Medi Campus, 32, Dongguk-ro, Ilsan Dong-gu, Goyang-si, Gyeonggi-do, Korea. E-mail:smkim@dongguk.edu
Abstract: In this study, several variables related to the thickness
of the retinal layer were measured via optical coherence tomography (OCT),
and the clinical applicability of such measurements was evaluated to
differentiate between diabetic cystoid macular edema (DCME) and
postoperative cystoid macular edema (PCME). To this end, a total of 120
subjects (30 healthy individuals, 60 DCME patients, and 30 PCME patients)
were selected as the experimental subjects. The six risk factors included
the thicknesses for the total retina (TR), the inner retina (IR), the
photoreceptor outer segments (POS), the outer retina (OR), the ganglion cell
(GC), and the retinal nerve fiber layer (RNFL), and these were estimated by
using a hierarchical approach through observations from OCT image scans. All
of the risk factors were obtained from the OCT images captured within a 6-mm
diameter from the center of the macula. The results of the experiment
indicated that the proposed method can reliably differentiate between DCME
and PCME. Moreover, as DCME and PCME progressed, the most significant
deterioration was found in the central macular region. These results suggest
that the proposed method has clinical applicability for the diagnosis of
DCME and PCME from OCT images.
