Doppler Monte Carlo simulations of light scattering in tissue to support laser-Doppler perfusion measurements

Article type: Research Article

Authors: de Mul, F.F.M. | Steenbergen, W. | Greve, J.

Affiliations: University of Twente, Department of Applied Physics, Enschede, Netherlands. Tel./Fax: xx 31 53 489 3160/1105; E-mail: mul@tn.utwente.nl

Abstract: Doppler Monte Carlo (DMC) simulations of the transport of light through turbid media, e.g., tissue, can be used to predict or to interpret measurements of the blood perfusion of tissue by laser-Doppler perfusion flowmetry. We describe the physical and mathematical background of Doppler Monte Carlo calculations, and present some comparisons with measurements, performed with experimental flow models, built to mimic skin tissue characteristics and for the calibration of perfusion instruments, which are important goals of the Biomed-I concerted action. The measurements deal with coherence effects.

Keywords: Microcirculation, laser-Doppler, flowmetry, blood, perfusion, Monte Carlo, simulations, tissue

DOI: 10.3233/THC-1999-72-308

Journal: Technology and Health Care, vol. 7, no. 2-3, pp. 171-183, 1999