Affiliations: Physics of Nanostructured Systems Department, National Institute for R&D of Isotopic and Molecular Technologies, Cluj-Napoca, Romania | Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania | Faculty of Physics, Babes–Bolyai University, Cluj-Napoca, Romania
Note: [] Corresponding author: I. Bratu, Physics of Nanostructured Systems Department, National Institute for R&D of Isotopic and Molecular Technologies, P.O. Box 700, R-400234 Cluj-Napoca, Romania. E-mail: ibratu@gmail.com.
Abstract: The aim of the present paper was to obtain new solid forms of Norfloxacin. For this purpose Norfloxacin was recrystallized from: acetic acid and its mixtures with several organic solvents. By recrystallization of Norfloxacin from acetic acid and from its mixture with several organic solvents a new solvate was found. To evidence this new solid form of Norfloxacin different investigation techniques were used: powder X-ray diffraction, FTIR, DSC, 13C NMR spectroscopy and mass spectrometry. The solvate is consisting on Norfloxacin and acetic acid in 1:1 molar ratio and crystallizes in triclinic system and the cell parameters were determined also.
