Searching for just a few words should be enough to get started. If you need to make more complex queries, use the tips below to guide you.
Article type: Review Article
Authors: Yana, Metehana | Tutuola, Fadodunb | Westwater-Wood, Sarahc | Kavlak, Erdoğand; *
Affiliations: [a] University of Karabuk, Faculty of Health Science Karabük, Turkey | [b] Queens Medical Centre, Nottingham University Hospital NHS, Nottingham, UK | [c] University of Nottingham, Faculty of Medicine and Health Sciences, Nottingham, UK | [d] Pamukkale University, School of Physical Therapy and Rehabilitation, Denizli, Turkey
Correspondence: [*] Address for correspondence: E. Kavlak, Pamukkale University, School of Physical Therapy and Rehabilitation, Kınıklı Kampüsü, 20070 Denizli, Turkey. Tel.: +90 258 2964257; Fax: +90 258 2964246; E-mail: kavlake@hotmail.com.
Abstract: BACKGROUND:To assess treatment effect of lower limb botulinum toxin type A (BTX-A) in combination with physiotherapy approaches on gross motor functions in children with cerebral palsy compared with only physiotherapy treatment. OBJECTIVE:The purpose of this review was to analyze the efficacy botulinum toxin a lower limb injections in addition to physiotherapy approaches in children with cerebral palsy. METHODS:A literature search was conducted in the following databases: Cochrane, PEDro, PubMed, MEDLINE, AMED and EMBASE. The searches were limited to the period from July 2009 to July 2015. The intervention had to contain BTX-A into the lower limb plus physiotherapy approaches and be compared with only physiotherapy. The methodological quality and clinical relevance were independently assessed by the authors. RESULTS:The database search resulted in a total of 1521 studies, of which 4 (Level II of evidence) trials were included in this review. The population represented by were age between from 11 month to 15 years. Overall there were 153 children all diagnosed with CP (87 Male, 66 Female). CONCLUSIONS:The use of BTX-A injections in addition to physiotherapy approaches seems to have positive effect on spasticity and ROM. However, the question of whether the treatment of BTX-A plus physiotherapy has a greater improvement on functional capacity, such as gross motor function or gait parameter than only physiotherapy treatments, was inconclusive. Further investigation by rigorous studies is required.
Keywords: Physiotherapy, cerebral palsy, botulinum toxin type A, GMFCS, GMFM
DOI: 10.3233/NRE-182581
Journal: NeuroRehabilitation, vol. 44, no. 2, pp. 175-189, 2019
IOS Press, Inc.
6751 Tepper Drive
Clifton, VA 20124
USA
Tel: +1 703 830 6300
Fax: +1 703 830 2300
sales@iospress.com
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
IOS Press
Nieuwe Hemweg 6B
1013 BG Amsterdam
The Netherlands
Tel: +31 20 688 3355
Fax: +31 20 687 0091
info@iospress.nl
For editorial issues, permissions, book requests, submissions and proceedings, contact the Amsterdam office info@iospress.nl
Inspirees International (China Office)
Ciyunsi Beili 207(CapitaLand), Bld 1, 7-901
100025, Beijing
China
Free service line: 400 661 8717
Fax: +86 10 8446 7947
china@iospress.cn
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
如果您在出版方面需要帮助或有任何建, 件至: editorial@iospress.nl