Searching for just a few words should be enough to get started. If you need to make more complex queries, use the tips below to guide you.
Article type: Research Article
Authors: Lampropoulos, Konstantinos M.a | Bonou, Mariaa | Bountziouka, Vassilikib | Evangelopoulos, Angelosc | Giotopoulou, Amaliab | Vallianou, Nataliad | Avgerinos, Petera | Panagiotakos, Demosthenesb | Barbetseas, Johna
Affiliations: [a] “Polyclinic” General Hospital, 3 Pireos Ave., Omonia Sq., 10552 Athens, Greece. e-mail: konlampropoulos@yahoo.gr | [b] Department of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece | [c] Roche Diagnostics (Hellas) SA, Athens, Greece | [d] “Evangelismos”, General Hospital Athens, Athens, Greece
Abstract: Studying dietary patterns and its relation to the development of various chronic diseases have received much interest during the past years, since they capture a holistic approach of true diet. Haptoglobin (Hp) has been associated with cardiovascular heart disease risk especially with acute myocardial infarction, coronary and peripheral artery disease, stroke, and heart failure. This study aimed to evaluate the relationship between dietary patterns and Hp blood levels among apparently healthy adults. During 2009, 490 volunteers (46 ± 16 years, 40 % male) were consecutively enrolled to the study (participation rate 85 %). Biochemical analyses were performed through established procedures, after 12 h fasting. Anthropometric, lifestyle and dietary characteristics were also recorded to account for potential confounders. Principal components analysis (PCA) was the data-driven technique to extract the dietary patterns. Pattern analysis revealed eight dietary patterns through the application of PCA; however, four of them were considered nutritionally important as they explained 35 % of total variance in food consumption (“Western diet”, “Mediterranean diet”, “Meat and bakery products” and “Alcohol and stimulants pattern”). The fourth pattern (alcohol and stimulants intake) has been characterised by intake of alcoholic drinks (wine, beer, and spirits) and stimulants (coffee and tea). Adherence to the latter pattern was associated with reduced Hp levels (b ± SE −5.9 ± 2.7, p = 0.03), adjusted for age, sex, body mass index, physical activity, and smoking habits. However, multi-adjusted analysis revealed that the individual effect of alcohol or stimulants on lowering Hp levels was not significant (p = 0.27 and p = 0.05, respectively). Moderate drinking of alcoholic drinks and stimulants seems to be associated with lower haptoglobin levels, suggesting another potential mechanism for the health benefits achieved through alcohol and stimulants drinking.
Keywords: Haptoglobin, Alcohol, Dietary pattern, Healthy individuals
DOI: 10.3233/s12349-013-0122-6
Journal: Mediterranean Journal of Nutrition and Metabolism, vol. 6, no. 2, pp. 127-133, 2013
IOS Press, Inc.
6751 Tepper Drive
Clifton, VA 20124
USA
Tel: +1 703 830 6300
Fax: +1 703 830 2300
sales@iospress.com
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
IOS Press
Nieuwe Hemweg 6B
1013 BG Amsterdam
The Netherlands
Tel: +31 20 688 3355
Fax: +31 20 687 0091
info@iospress.nl
For editorial issues, permissions, book requests, submissions and proceedings, contact the Amsterdam office info@iospress.nl
Inspirees International (China Office)
Ciyunsi Beili 207(CapitaLand), Bld 1, 7-901
100025, Beijing
China
Free service line: 400 661 8717
Fax: +86 10 8446 7947
china@iospress.cn
For editorial issues, like the status of your submitted paper or proposals, write to editorial@iospress.nl
如果您在出版方面需要帮助或有任何建, 件至: editorial@iospress.nl