Development of metal ion promoted alcoholysis as a rapid methodology for the destruction of organophosphorus CW agents, their simulants and pesticides

Issue title: Sensing and Destroying Chemical Weapons and Pesticides Based on the Symposium at the 238th American Chemical Society Meeting Washington DC, USA, August 18–19, 2009

Article type: Research Article

Authors: Neverov, Alexei A. | Brown, R. Stan

Affiliations: Department of Chemistry, Queen's University, Kingston, Ontario, Canada

Note: [] Corresponding author: Department of Chemistry, Queen's University, Kingston, Ontario, Canada. E-mail: rsbrown@chem

Abstract: Metal-catalyzed alcoholysis has proven to be an effective strategy for the rapid decomposition of neutral organophosphate triesters, phosphonates, phosphorothioates and phosphorothionates, as well as several organophosphate chemical weapons of the G and V-agent classes. This article reviews the development of the chemical methodology starting from early studies with phosphate triesters up to the most recent studies dealing with the testing for decontamination of live chemical agents.

Keywords: Metal ion catalyzed alcoholysis, pesticides, chemical weapons, decontamination

DOI: 10.3233/MGC-2010-0029

Journal: Main Group Chemistry, vol. 9, no. 3-4, pp. 265-281, 2010