Comparative study of abdominal CT enhancement in overweight and obese patients based on different scanning modes combined with different contrast medium concentrations
Affiliations: [a]
Affiliated Hospital of Hebei University/Clinical Medical College, Hebei University, Baoding, China
| [b] Hebei Key Laboratory of Precise Imaging of Inflammation Related Tumors, Baoding, China
Correspondence:
[*]
Corresponding author: Yong-Xia Zhao, Department of Radiology, Affiliated Hospital of Hebei University, No. 212 Yuhua East Road, Baoding 071000, China. Tel.: +86 15131221591; E-mail: zyx_zyx999@163.com.
Abstract: PURPOSE:To compare image quality, iodine intake, and radiation dose in overweight and obese patients undergoing abdominal computed tomography (CT) enhancement using different scanning modes and contrast medium. METHODS:Ninety overweight and obese patients (25 kg/m2≤body mass index (BMI)< 30 kg/m2 and BMI≥30 kg/m2) who underwent abdominal CT-enhanced examinations were randomized into three groups (A, B, and C) of 30 each and scanned using gemstone spectral imaging (GSI) +320 mgI/ml, 100 kVp + 370 mgI/ml, and 120 kVp + 370 mgI/ml, respectively. Reconstruct monochromatic energy images of group A at 50–70 keV (5 keV interval). The iodine intake and radiation dose of each group were recorded and calculated. The CT values, contrast-to-noise ratios (CNRs), and subjective scores of each subgroup image in group A versus images in groups B and C were by using one-way analysis of variance or Kruskal–Wallis H test, and the optimal keV of group A was selected. RESULTS:The dual-phase CT values and CNRs of each part in group A were higher than or similar to those in groups B and C at 50–60 keV, and similar to or lower than those in groups B and C at 65 keV and 70 keV. The subjective scores of the dual-phase images in group A were lower than those of groups B and C at 50 keV and 55 keV, whereas no significant difference was seen at 60–70 keV. Compared to groups B and C, the iodine intake in group A decreased by 12.5% and 13.3%, respectively. The effective doses in groups A and B were 24.7% and 25.8% lower than those in group C, respectively. CONCLUSION:GSI +320 mgI/ml for abdominal CT-enhanced in overweight patients satisfies image quality while reducing iodine intake and radiation dose, and the optimal keV was 60 keV.
