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Article type: Research Article
Authors: Zhang, Chaoa; * | Huang, Yu-Qinb | Liu, Zhi-Longa
Affiliations: [a] Department of Ultrasonic, the People Hospital of Shanxi, Taiyuan, China | [b] Department of Ultrasonic, the First Affiliated Hospital of Shanxi Medical University, Taiyuan, China
Correspondence: [*] Corresponding author: Chao Zhang, MD., Department of Ultrasonic, Shanxi Provincial People’s Hospital, 29 Shuangtaisi Street, Yingze District, Taiyuan, Shanxi 030001, China. Tel.: +86 0351 4960079; Fax: +86 0351 4960079; E-mail: zhangc5268740@163.com.
Abstract: OBJECTIVE:To evaluate diagnostic value of Thyroid Imaging Reporting and Data System published by American College of Radiology (ACR TI-RADS) in 2017, ultrasound-guided fine-needle aspiration (US-FNA), and the combination of both methods in differentiation between benign and malignant thyroid nodules. METHODS:The data of US-FNA and ACR TI-RADS are collected from 159 patients underwent thyroid surgery in our hospital, which include a total of 178 thyroid nodules. A Bethesda System for Reporting Thyroid Cytopathology category of ≥IV and an ACR TI-RADS category ≥4 are regarded as diagnosis standards for malignancy in US-FNA and ACR TI-RADS, respectively. The pathological results after surgery are considered as the gold standard. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of the ACR TI-RADS, US-FNA and the combination of both methods for the differential diagnosis of thyroid nodules are calculated, respectively. RESULTS:The sensitivity, specificity and accuracy of ACR TI-RADS are 85.4%, 37.5%and 72.5%, respectively. The sensitivity, specificity and accuracy of US-FNA are 70.0%, 100%and 78.1%, respectively. After combining these two methods, the sensitivity, specificity and accuracy increase to 99.23%, 37.50%and 82.58%, respectively. The sensitivity of ACR TI-RADS is higher than that of US-FAN, and the sensitivity of combining these two methods is also higher than that of using ACR TI-RADS and US-FNA alone. CONCLUSION:The established ACR TI-RADS can help in selecting the target during nodule puncture, while the combination of ACR TI-RADS and US-FAN can further improve diagnostic ability for detecting malignant thyroid nodules.
Keywords: ACR TI-RADS, ultrasound imaging, fine-needle aspiration biopsy (FNAB), thyroid nodule, differential diagnosis
DOI: 10.3233/XST-210949
Journal: Journal of X-Ray Science and Technology, vol. 29, no. 6, pp. 1113-1122, 2021
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