Affiliations: [a] Department of Radiology, The Second Affiliated Hospital of Kunming Medical University, China
| [b] Department of Radiology, Wuhan Asian Heart Hospital, China
| [c] Department of Cardiology, The Second Affiliated Hospital of Kunming Medical University, China
| [d] Department of Epidemiology and Biostatistics, School of Public Health of Kunming Medical University, China
| [e] Biomedical Engineering Research Center, Kunming Medical University, China
| [f] Department of Radiology, Beijing An Zhen Hospital, Capital Medical University, Beijing, China
Correspondence:
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Corresponding author: Xiaohai Ma, Department of Radiology, Beijing An Zhen Hospital, Capital Medical University, No. 2 Anzhen Road, Chaoyang District, 100029, Beijing, China. Tel.: +86 01084005289; Fax: +86 010 84005289; E-mail:maxi8238@yahoo.com.
Note: [1] Xinxiang Zhao and Renhui Cai are co-first authors.
Abstract: OBJECTIVE:Correlation between myocardial infarction (MI) scar by cardiac magnetic resonance and the Lown’s classification of ventricular premature beats (VPBs) is poorly understood. This study aims to investigate the correlation between the MI scar characteristics by delayed-enhancement magnetic resonance imaging (DE-MRI) and the Lown’s classification of VPBs. METHODS:Sixty-five patients, in the convalescence stage and consolidation phase of MI, were included in this retrospective study. All patient were divided into VPBs group (n = 39) and non-VPBs group (n = 26 patients) according to the clinical diagnostic criteria of Universal Definition of MI scar. VPBs patients were assigned to Lown’s I-II group and Lown’s III-IV subgroup in accordance with the Lown classification criteria. Cardiac function parameters and MI scar characteristics were detected by cardiac magnetic resonance (CMR) and DE-MRI, respectively. RESULTS: Lown’s classification was negatively correlated with left ventricular ejection fraction (LVEF), peak ejection rate (PER) and peak filling rate (PFR) (–0.724, –0.628, –0.559), and positively correlated with MI area, MI integral, MI segments number and left ventricular end systolic volume (LVESV) (0.673, 0.655, 0.586, and 0.514), respectively. CONCLUSIONSThe study indicated that MI area and MI integral were strongly associated with Lown’s classification.
