Affiliations: [a] Shandong Medical Imaging Research Institute, Shandong University School of Medicine, Huaiyin District, Jinan City, Shandong Province, China
| [b]
Binzhou Medical College Hospital, Bincheng District, Binzhou City, Shandong Province, China
| [c]
Binzhou Medical College, Guanhai Road, Laishan District, Yantai City, Shandong Province, China
| [d] Department of Operational Medicine, Tianjin Institute of Environmental and Operational Medicine, Heping District, Tianjin, China
Correspondence:
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Corresponding authors: Chuan-ting Li, Shandong Medical Imaging Research Institute, Shandong University School of Medicine, Huaiyin District, Jinan City, Shandong Province 250021, China. E-mail: lichuanting@yeah.net and Quan-sheng Gao, Department of Operational Medicine, Tianjin Institute of Environmental and Operational Medicine, No.1 Dali Road, Heping District, Tianjin 300050, China. E-mail: gaoquansheng2002@163.com.
Abstract: OBJECTIVE:To evaluate the relationship of microhemorrhage on susceptibility-weighted imaging (SWI) with the severity of clinical symptoms and the prognosis of viral encephalitis. MATERIALS AND METHODS:Thirty patients with clinically diagnosed viral encephalitis were divided into three groups according to the Glasgow Coma Scale (GCS) and the condition of recovery namely, Group I (n = 12): Glasgow Coma Scale (GCS)≥13 and recovered with no sequelae; Group II (n = 11): GCS 9–12 and recovered with some sequelae; Group III (n = 7): GCS 3–8 and recovered with more severe sequelae. The microhemorrhage detectability on SWI and conventional MR imaging in these three groups was compared and their correlations with different seriousness of clinical symptoms and prognosis were analyzed. RESULTS:There was a significant difference in microhemorrhage volume among different MR sequences (p < 0.05). SWI was more sensitive to detect microhemorrhage than conventional MR imaging techniques. Microhemorrhages on SWI were significantly different among the three groups (p < 0.01). The volume of microhemorrhage on SWI was well correlated with the degree of clinical symptoms and the prognosis of viral encephalitis. CONCLUSION:SWI can be used to detect microhemorrhage in patients with viral encephalitis. Assessment of microhemorrhage with SWI can provide useful information for the prognosis evaluation of viral encephalitis.
