Application of magnetic resonance imaging in diagnosis of Uterus Cervical Carcinoma

Issue title: Impact of advanced parallel or cloud computing technologies for image guided diagnosis and therapy

Guest editors: Kelvin K.L. Wong, Simon Fong and Defeng Wang

Article type: Research Article

Authors: Peng, Jidong^a | Wang, Weiqiang^{b; 1} | Zeng, Daohui^{c; *}

Affiliations: [a] Department of Radiology, Ganzhou People’s Hospital, Jiangxi, China | [b] Department of Gynecology, The Northwest Women and Children’s Hospital, Xi-an, China | [c] Department of Radiology, First Affiliated Hospital of Guangzhou University of TCM, Guangzhou, Guangdong, China

Correspondence: [*] Corresponding author: Daohui Zeng, Department of Radiology, First Affiliated Hospital of Guangzhou University of TCM, Guangzhou, Guangdong 510405, China. E-mail: Zengdh1971@163.com.

Note: [1] Co-first author: Weiqiang Wang.

Abstract: BACKGROUND AND OBJECTIVE: Effective treatment of Uterus Cervical Carcinoma (UCC) rely heavily on the precise pre-surgical staging. The conventional International Federation of Gynecology and Obstetrics (FIGO) system based on clinical examination is being applied worldwide for UCC staging. Yet its performance just appears passable. Thus, this study aims to investigate the value of applying Magnetic Resonance Imaging (MRI) with clinical examination in staging of UCC. MATERIALS AND METHODS: A retrospective dataset involving 164 patients diagnosed with UCC was enrolled in this study. The mean age of this study population was 46.1 years (range, 28–#x2013;75 years). All patients underwent operations and UCC types were confirmed by pathological examinations. The tumor stages were determined by two experienced Gynecologist independently based on FIGO examinations and MRI. The diagnostic results were also compared with the post-operative pathologic reports. Statistical data analysis on diagnostic performance was then done and reported. RESULTS: The study results showed that the overall accuracy of applying MRI in UCC staging was 82.32%, while using FIGO staging method, the staging accuracy was 59.15%. CONCLUSIONS: MRI is suitable to evaluate tumor extent with high accuracy, and it can offer more objective information for the diagnosis and staging of UCC. Compared with clinical examinations based on FIGO, MRI illustrated relatively high accuracy in evaluating UCC staging, and is worthwhile to be recommended in future clinical practice.

Keywords: Magnetic Resonance Imaging, diagnosis, Uterus Cervical Carcinoma

DOI: 10.3233/XST-17254

Journal: Journal of X-Ray Science and Technology, vol. 25, no. 2, pp. 205-211, 2017