Affiliations: College of Precision Instrument and Optoelectronics
Engineering, Tianjin University, Tianjin, China | Tianjin Key Laboratory of Biomedical Detecting
Techniques and Instruments, Tianjin, China
Note: [] Corresponding author: Huijuan Zhao, College of Precision
Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072,
China. Tel.: +86 022 27404209; Fax: +86 022 27404209; E-mail: huijuanzhao@tju.edu.cn
Abstract: Endoscopic diffuse optical tomography (DOT) is a new medical imaging
modality with the potential applications in functional imaging of the internal
organs. To cut down the measurement time and the computation burden of image
reconstruction, in this paper, we developed the image reconstruction algorithm
with the partial measurement in the effective detection range (EDR) of a
tubular tissue and the corresponding endoscopic imaging system with a novel
endoscopic probe for flexibly selecting the detection sites. For a typical
inner size and optical properties of the cervix, it is found that EDR is less
than half of the inner circumference. Comparing to the traditional method, the
adoption of EDR results in a reduction of more than a factor of two in the time
cost for a measurement cycle and for the total iteration reconstruction. Images
reconstructed from the simulation data demonstrate that the proposed method
achieves equivalent image quality to that obtained from the complete data set.
The images reconstructed from the EDR measurements on cervix-like solid
phantoms show that both the location and size of the targets are reconstructed
correctly. The proposed method will be useful to the development of endoscopic
DOT technologies for cancer detection in tubular organs including cervix.
