Affiliations: Department of Biomedical Imaging and Radiological
Science, China Medical University, Taiwan, China | Department of Biomedical Imaging and Radiological
Sciences, National Yang-Ming University, Taiwan, China | National Center for High-Performance Computing,
Hsinchu, Taiwan, China | Power Mechanical Engineering Department, National
Tsing Hua University, Taiwan, China | Department of Medical Imaging and Radiological
Sciences, I-Shou University, Taiwan, China
Note: [] Corresponding author: Tzung-Chi Huang, Department of Biomedical
Imaging and Radiological Science, China Medical University, Taiwan 91,
Hsueh-Shih Road, Taichung City, Taiwan 404, China. Tel.: +886 422 053 366 #
7805; E-mail: tzungchi.huang@mail.cmu.edu.tw
Abstract: Background and purpose: Computational fluid dynamics method (CFDM)
and optical flow method (OFM) effectively provide the hemodynamic information
based on the digital subtraction angiogram (DSA). However, the quantitative
analysis in comparison of CFDM and OFM is still absent. The goal of this study
is to apply CFDM and OFM in quantitative analysis of stenting treatment. Material and method: A left carotid stenosis patient underwent
stenting of percutaneous transluminal angioplasty was analyzed as an example.
CFDM and OFM for hemodynamic analysis on digital subtraction angiography before
and after stenting treatment were presented. Results: Improvement gains of blood flow velocities on left internal
carotid artery after stenting treament for different initial conditions on the
common carotid artery were 1.91 ∼ 2.13, 1.62 ∼ 2.09, and 0.69 by CFDM
with Newtonian and non-Newtonian fluids and OFM, respectively. With the CFDM
analysis, the flow mapping by OFM using time resolved DSA data on the fly to
estimate hemodynamic significance of a cervical carotid stenosis was
explained. Conclusion: Quantificative blood flow estimations by CFDM and OFM to
evaluate the treatment outcomes to patient with carotid stenosis are practical.
Both methods are able to provide quantitative information of blood flow for
stenting treatment. It is advantagious to use both methods in treatment
evaluation.
