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Article type: Research Article
Authors: Lau, Andy | Chen, Yong | Ahmad, Salahuddin
Affiliations: Department of Radiation Oncology, Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
Note: [] Corresponding author: Salahuddin Ahmad, Ph.D., Department of Radiation Oncology, Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center 800 N.E. 10th St., OKCC L100, Oklahoma City, OK 73104, USA. Tel.: +1 405 271 5641 ext. 37833; Fax: +1 405 271 8297; E-mail: salahuddin-ahmad@ouhsc.edu
Abstract: A Monte Carlo application is developed to investigate the yields of positron-emitting nuclei (PEN) used for proton and carbon ion range verification techniques using the GEANT4 Toolkit. A base physics list was constructed and used to simulate incident proton and carbon ions onto a PMMA or water phantom using pencil like beams. In each simulation the total yields of PEN are counted and both the PEN and their associated positron depth-distributions were recorded and compared to the incident radiation's Bragg Peak. Alterations to the physics lists are then performed to investigate the PEN yields dependence on the choice of physics list. In our study, we conclude that the yields of PEN can be estimated using the physics list presented here for range verification of incident proton and carbon ions.
Keywords: Positron emitting nuclei, radiation therapy, Geant4 simulation
DOI: 10.3233/XST-2012-0340
Journal: Journal of X-Ray Science and Technology, vol. 20, no. 3, pp. 317-329, 2012
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