Affiliations: CT/Micro-CT Laboratory, Department of Radiology,
University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA | E-mail:James-R-Bennett@uiowa.edu | Electrical and Computer Engineering, University of
Iowa, 4316 Seamans Center, Iowa City, IA 52242, USA. E-mail:
Er-Wei-Bai@uiowa.edu | Department of Interventional Radiology, Cedar Valley
Medical Specialists, 602 Ansborough Ave, Waterloo, IA 50604, USA | E-mail: Ge-Wang@uiowa.edu
Abstract: About two million peripheral angiographies are performed annually in
the United States, hence a reduction in exposure would yield significant
healthcare benefits. The synchronization of bolus traveling, the table motion,
and the fluoroscopic imaging chain can be highly effective for dose reduction
in Digital Subtraction Angiography (DSA) by minimizing the field-of-view
according to the vascular anatomy of the region traveled by the bolus. The goal
of this paper is to demonstrate the feasibility of adjusting the field-of-view
while tracking the contrast bolus, thus reducing the dosage of both the bolus
and the radiation. The speed of the bolus is respectively estimated in the
systole and diastole stages. An EKG-gated Hammerstein model is used to predict
the bolus chasing speed. A real-time algorithm is designed to extract the bolus
dynamics, and define the field of view transversely and longitudinally. A limb
stabilization technique is also presented to suppress any significant image
misalignment. Our simulation results show that the proposed techniques are
promising for clinical applications.
Keywords: digital subtraction angiography, real-time imaging
