Affiliations: Department of Radiology, Johns Hopkins University
School of Medicine, Baltimore, MD, USA
Note: [] Corresponding author: Xiaoming Yang, MD, PhD, Department of
Radiology, Johns Hopkins University School of Medicine, Traylor Building, Room
330, 720 Rutland Avenue, Baltimore, MD 21205, USA. Tel.: +1 410 502 6960; Fax:
+1 443 287 6730; E-mail: xyang@mri.jhu.edu
Abstract: Vascular gene therapy is a potential promising treatment for
atherosclerotic disease. Imaging of vascular gene therapy is essential for the
assessment of the success of the therapeutic strategy. Several imaging
techniques, including MRI, ultrasound, and optical imaging, have been evaluated
to monitor, enhance, and track vascular gene delivery,
transfection/transduction, and expression. This review summarizes the current
status of applying these techniques in the imaging of vascular gene
therapy.
Keywords: gene therapy, arteries, magnetic resonance imaging, ultrasonography, optical imaging
