Postural stability and handicap of dizziness after preoperative vestibular ablation and vestibular prehabilitation in patients undergoing vestibular schwannoma resection

Article type: Research Article

Authors: Fellmann, Jonas^{a; b; 1; *} | Bächinger, David^{a; b; 1} | Dalbert, Adrian^{a; b} | Röösli, Christof^{a; b} | Huber, Alexander^{a; b} | Wettstein, Vincent G.^{a; b}

Affiliations: [a] Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland | [b] University of Zurich, Zurich, Switzerland

Correspondence: [*] Corresponding authors. Jonas Fellmann, MD, Department of Otorhinolaryngology, University Hospital Zurich, Frauenklinikstrasse 24, 8091 Zurich, Switzerland. Tel.: +41 44 255 55 50; E-mail: jonas.fellmann@usz.ch.

Note: [1] These authors contributed equally to this work.

Abstract: BACKGROUND:Surgical treatment of vestibular schwannoma (VS) leads to acute ipsilateral vestibular loss if there is residual vestibular function before surgery. To overcome the sequelae of acute ipsilateral vestibular loss and to decrease postoperative recovery time, the concept of preemptive vestibular ablation with gentamicin and vestibular prehabilitation before surgery has been developed (“vestibular prehab”). OBJECTIVE:Studying postural stability during walking and handicap of dizziness over a 1-year follow-up period in VS patients undergoing vestibular prehab before surgical treatment of VS. METHODS:A retrospective review of consecutive patients with a diagnosis of a VS undergoing surgical therapy from June 2012 to March 2018 was performed. All patients were included with documentation of the length of hospital duration and the Dizziness Handicap Inventory (DHI) and the Functional Gait Assessment (FGA) assessed preoperatively as well as 6 weeks and 1 year postoperatively. RESULTS:A total 68 VS patients were included, of which 29 patients received preoperative vestibular ablation by intratympanic injection of gentamicin. Mean VS diameter was 20.2 mm (SD 9.4 mm) and mean age at surgery was 49.6 years (SD 11.5 years). Vestibular prehab had no effect on DHI and FGA at any time point studied. CONCLUSIONS:We found no effect of vestibular prehab on postural stability during walking and on the handicap of dizziness. These findings add to the body of knowledge consisting of conflicting results of vestibular prehab. Therefore, vestibular prehab should be applied only in selected cases in an experimental setting.

Keywords: Balance, dizziness, prehab, dizziness handicap inventory, functional gait assessment, gentamicin, rehabilitation, surgery, vestibular ablation

DOI: 10.3233/VES-200023

Journal: Journal of Vestibular Research, vol. 32, no. 1, pp. 49-56, 2022