Affiliations: Department of Physical Medicine and Rehabilitation, University of Colorado Denver and Children’s Hospital Colorado, Aurora, CO, USA
Correspondence:
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Corresponding author: Joyce L. Oleszek, Department of Physical Medicine and Rehabilitation, University of Colorado Denver and Children’s Hospital Colorado, 13123 E. 16 th Avenue, Aurora, CO 80045, USA. Tel.: +1 720 7772806/+1 303 7189917; E-mail: Joyce.oleszek@childrenscolorado.org.
Abstract: Botulinum toxin is frequently used as a therapeutic for a variety of non-FDA approved indications in children. This narrative literature review explores three off-label uses of botulinum toxin in pediatric conditions including congenital muscular torticollis, spastic trismus, and neonatal brachial plexus palsy. While more research is needed to establish treatment, dosing and localization guidelines for the use of botulinum toxin in these commonly treated conditions, available evidence is discussed.
