Affiliations: Department of Pediatrics, The Federal University of
Rio de Janeiro, Av Brigadeiro Trompowski S/N, Rio de Janeiro, Brazil | National Virus Reference Laboratory, Medical
Microbiology, University College Dublin, Belfield, Dublin 4, Ireland | Department of Microbiology, University College
Department of Dublin, Belfield, Dublin 4, Ireland
Note: [] Correspondence: Alexandra P. de Q. C. Araújo, M.D.,
PhD. Department of Pediatrics, The Federal University of Rio de Janeiro, Av
Brigadeiro Trompowski S/N, Rio de Janeiro, 21949-900, Brazil. Tel:
+55-21-24930792 E-mail: alexprufer@ufrj.br
Abstract: To investigate the role of cytomegalovirus (CMV) infection in the
pathogenesis of peripheral neuropathy in children with acquired
immunodeficiency syndrome (AIDS) a cross-sectional descriptive study was
conducted on a sample of nine children. Plasma samples were tested for CMV DNA
by two polymerase chain reaction assays (sensitivity limits of 400 and 10
copies/mls) respectively. While all nine were CMV seropositive all were
negative for viremia in both assays. CMV would appear not to be involved in
children with AIDS-associated sensory neuropathies. (J Pediatr Neurol 2004;
2(4): 219–223).
Keywords: cytomegalovirus, peripheral nervous system disease, child, HIV
