Intra-arterial thrombolysis in a child with acute basilar artery occlusion

Article type: Research Article

Authors: Chandratre, Saleel R. | Goddard, Tony | Morton, Richard | Whitehouse, William P.^;

Affiliations: Department of Pediatric Neurology, Nottingham University Hospitals NHS Trust, Nottingham, UK | Department of Neuroimaging, Nottingham University Hospitals NHS Trust, Nottingham, UK | Ronnie Mac Keith Centre, Derbyshire Children's Hospital, Derby, UK | School of Clinical Sciences, University of Nottingham, Nottingham, UK

Note: [] Correspondence: Dr. William P. Whitehouse, FRCP, Child Health, E Floor, East Block, Queen's Medical Centre, NG7 2UH, Nottingham, UK. Tel.: +44 (0) 115 924 9924; ext 63328; Fax: +44 (0) 115 823 0626; E-mail: william.whitehouse@nottingham.ac.uk

Abstract: We report a case of a child who suffered a left hemisphere arterial ischemic stroke due to basilar artery occlusion. He was treated with intra-arterial recombinant tissue plasminogen activator at six and a half hours after the onset of hemiparesis. There were no complications and he showed rapid neurological and neuroimaging improvement. Where facilities allow rapid assessment at a combined adult and pediatric neurosciences facility, intra-arterial recombinant tissue plasminogen activator should be considered, especially for posterior circulation thrombosis.

Keywords: Child, basilar occlusion, arterial ischemic stroke, thrombolysis

DOI: 10.3233/JPN-2011-0483

Journal: Journal of Pediatric Neurology, vol. 9, no. 3, pp. 391-396, 2011