Affiliations: Carman and Ann Adams Department of Pediatrics,
Children's Hospital of Michigan, Wayne State University, Detroit, MI, USA
Note: [] Correspondence: Dr. Madhvi Rajpurkar, Wayne State University,
Division of Pediatric Hematology Oncology, Children's Hospital of Michigan,
3901 Beaubien Blvd., Detroit, MI 48201, USA. Tel.: +1 313 745 5515; Fax: +1
313 745 5237; E-mail: mrajpurk@med.wayne.edu
Abstract: Pediatric stroke is a heterogeneous disorder and is associated with
significant morbidity and mortality in children. The role of thrombophilia is
becoming increasingly important in the pathogenesis of stroke but its effect on
clinical outcome and recurrence is not yet well defined. This review provides a
summary of current knowledge of thrombophilia in pediatric stroke.