Affiliations: Department of Pediatrics, Advanced Pediatric Center,
Postgraduate Institute of Medical Education & Research, Chandigarh,
India | Department of Nuclear Medicine, Postgraduate Institute
of Medical Education & Research, Chandigarh, India
Note: [] Correspondence: Prof. Pratibha Singhi, Chief of Neurology Unit,
Department of Pediatrics, Advanced Pediatric Center, PGIMER, Chandigarh,
160012, India. Tel.: +91 172 2755304; Fax: +91 172 2744401, 2745078; E-mail:
pratibhasinghi@yahoo.com
Abstract: Single photon emission tomography (SPECT) of the brain was studied
in 22 children with primary autism with varying degrees of severity. Fifteen
children had no perfusion abnormalities on SPECT imaging. Of the remaining
seven, decreased perfusion in the left frontoparietal cortex was seen in three,
and in the left inferior and medial frontal cortex in two children. No
correlation could be found between SPECT, electroencephalography, and magnetic
resonance imaging findings. Our findings are similar to those previously
reported in some studies, and present areas of further inquiry regarding
therapeutic intervention or diagnosis.
