Familial paroxysmal exertion induced dyskinesia with a good response to phenytoin

Article type: Research Article

Authors: Singhi, Pratibha | Mahajan, Vikas

Affiliations: Departments of Pediatrics, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Note: [] Correspondence: Pratibha Singhi, M.D., Professor and Chief, Pediatric Neurology and Neurodevelopment, Advanced Pediatrics Centre, Postgraduate Institute of Medical Sciences, Chandigarh -160012, India. Tel.: +91 1722755304; Fax: +91 1722744401; E-mail: psinghi@glide.net.in

Abstract: Paroxysmal dyskinesias are neurologic conditions characterized by sudden episodes of abnormal involuntary movements. Paroxysmal exertion induced dyskinesia is a rare condition characterized by abnormal involuntary movements on exercise, which get relieved with rest. In general, these movements are poorly responsive to medical treatment. We report one family in which all three male members are affected and had good response to phenytoin.

Keywords: Dyskinesia, paroxysmal, exercise, phenytoin

Journal: Journal of Pediatric Neurology, vol. 5, no. 4, pp. 347-350, 2007