Use of dexmedetomidine as adjunctive therapy for anti-N-methyl-D-aspartate receptor encephalitis

Article type: Research Article

Authors: Babbitt, Christopher J.^; | Lake, Jean | Levine, Glenn K.

Affiliations: Pediatric Critical Care, Miller's Children Hospital, Long California, CA, USA

Note: [] Corresponding author: Christopher J. Babbitt, Pediatric Critical Care, Miller's Children Hospital, Long California, CA 90808, USA.

Abstract: Anti-N-methyl-D-aspartate receptor encephalitis is a recently discovered disease that is more commonly being diagnosed in children. Patients often require intensive care and assisted ventilation due to agitation, abnormal movements, hypoventilation, seizures and autonomic instability. There is no consensus on which medicines are best suited to acutely treat this constellation of central nervous system symptoms. We present the first case report of using dexmedetomidine to treat this condition.

Keywords: Dexmedetomidine, encephalitis, seizures, anti-N-methyl-D-aspartate receptor

DOI: 10.3233/PIC-13064

Journal: Journal of Pediatric Intensive Care, vol. 2, no. 3, pp. 143-145, 2013