Affiliations: Department of Pediatrics, Duke Children's Hospital,
Duke University Medical Center, Durham, NC, USA | Department of Pediatrics, Division of Pediatric,
Critical Care Medicine, Duke Children's Hospital, Duke University Medical
Center, Durham, NC, USA | Department of Pediatrics, Division of Pediatric
Infectious Disease, Duke Children's Hospital, Duke University Medical Center,
Durham, NC, USA | Department of Surgery, Division of Neurosurgery, Duke
University Medical Center, Durham, NC, USA
Note: [] Correspondence: Dr. Andrew Stack, M.D, Department of
Pediatrics, Duke University Medical Center, DUMC Box 3046, Durham, NC 27710,
USA. Tel.: +1 919 681 8111; Fax: +1 919 620 5333; E-mail: andrew.stack@duke.edu
Abstract: We report the first case of a previously healthy term 5 week old
infant with no known risk factors who developed a frontal lobe abscess from
community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA). To
date, only 16 cases of invasive CA-MRSA with central nervous system involvement
have been previously described, but the incidence of CA-MRSA has surged within
the last decade, creating a growing impact on public health. Increasing numbers
of invasive infections caused by CA-MRSA in previously healthy individuals is
of particular concern, and the highest rates of these infections are in
children. As CA-MRSA continues to spread and develop further antibiotic
resistance, cases of invasive diseases as described in this report may become more common.
