Affiliations: Department of Pediatrics, International Goodwill
Hospital, Yokohama, Kanagawa, Japan | Department of Pediatrics, Juntendo University School
of Medicine, Hongo, Bunkyo-ku, Tokyo, Japan | Department of Neurology, Kanagawa Children's Medical
Center Yokohama, Kanagawa, Japan
Note: [] Correspondence: Dr. Akihisa Okumura, MD, Department of
Pediatrics, Juntendo University, School of Medicine, 2-1-1 Hongo, Bunkyo-ku,
Tokyo,113-8421, Japan. Tel.: +81 3 3813 3111; Fax: +81 3 5800 1580; E-mail: okumura@juntendo.ac.jp
Abstract: A patient had recurrent pyrexia since 17 days of age followed by
convulsions. At 20 days of age, cerebrospinal fluid (CSF) analysis showed mild
pleocytosis, whereas bacterial culture of blood and CSF was negative and
computed tomography was unremarkable. Campylobacter fetus grew from CSF
sampled at 22 days of age and head computed tomography revealed low-density
area in the left frontal lobe. The patient was diagnosed as having focal
cerebritis and treated with intravenous ampicillin and cefotaxime successfully.
Although West syndrome developed at 4 months of age, his psychomotor
development was within normal range. Our patient shows that neonatal C.
fetus infection can cause focal cerebritis.