Affiliations: Department of Pediatrics, Acute and Critical Care
Programs, University of British Columbia, British Columbia, Canada | Department of Critical Care Medicine, University of
Pittsburgh, Pittsburgh, USA
Note: [] Correspondence: Niranjan Kissoon, MD, CPE, University of British
Columbia, British Columbia Children's Hospital, Room K4-105, 4480 Oak Street,
Vancouver, British Columbia V6H 3V4, Canada. Tel.: +604 875 2507; Fax: +604 875
3076; E-mail: nkissoon@cw.bc.ca
Abstract: Sepsis and septic shock are major contributors to mortality in
children worldwide. While many factors may contribute to poor outcomes,
resource limitations play a role in developing countries. However, early
recognition and aggressive therapy using simple measures can reverse shock in
most children. Indeed great gains have been realized in some areas with limited
resources. In this manuscript, we outline the treatment of sepsis in children
based on the resources available in various countries. This approach forms the
basis of the World Federation of Pediatric Intensive and Critical Care
Societies sepsis initiatives. An invitation is extended to participate in this
global sepsis initiative.
