Affiliations: Children's Hospital and Regional Medical Center,
Seattle, WA, USA
Note: [] Correspondence: Karen Murray, MD, Director, Hepatobiliary
Program, Division of Gastroenterology and Nutrition, Children's Hospital and
Regional Medical Center, 4800 Sand Point Way NE, P.O. Box 5371, Mail Stop
A5950, Seattle, WA 98105, USA. Tel.: +1 206 987 2587; Fax: +1 206 987 2721;
E-mail: Karen.Murray@seattlechildrens.org
Abstract: Chronic hepatitis C viral infection represents a worldwide viral
epidemic. The natural course of hepatitis C virus is less understood in the
pediatric population, although fewer children progress to cirrhosis and
end-stage liver disease than adults infected. In the last five years,
epidemiological and clinical research involving hepatitis C virus-infected
children has raised interesting observations regarding the differences in
transmission, natural history, and response to treatment in this
population.