Affiliations: [a]
Department of Neurology, University of California San Francisco, CA, USA
| [b] Verily Life Sciences, Mountain View, CA, USA
| [c] Department of Neurosurgery, University of California San Francisco, CA, USA
Correspondence:
[*]
Correspondence to: Svjetlana Miocinovic, MD, PhD, Emory University, Department of Neurology, 12 Executive Park NE, Atlanta, GA 30329, USA. Tel.: +1 404 712 9065; Fax: +1 404 727 0803; E-mail: svjetlana.miocinovic@emory.edu.
Abstract: We demonstrate the feasibility of estimating clinical tremor scores using an eating utensil with motion-sensing and tremor-cancellation technology in thirteen patients with tremor. Three experts scored hand tremor using the modified Fahn- Tolosa-Marin (FTM) scale. A linear model was trained to estimate tremor severity using the recorded motion signals. The average neurologist FTM score was 1.6±0.7 for PD and 2.6±0.7 for ET patients. The average model score was 1.6±0.7 for PD and 2.6±0.6 for ET. Correlation coefficient between the clinical and model tremor scores was 0.91 (p < 0.001). Motion data from an instrumented eating utensil accurately derived tremor ratings enabling practical, objective daily monitoring.
