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Article type: Research Article
Authors: Chawla, S.a; * | Elbakoush, F.b; 1 | Natarajan, G.a | Dwaihy, M.b | Berry, A.a | Ravindranath, Y.c | Bhambhani, K.c | Narayan, S.B.d
Affiliations: [a] Division of Neonatal Perinatal Medicine, Hutzel Women’s Hospital and Children’s Hospital of Michigan, Wayne State University, Detroit, MI, USA | [b] Department of Pediatrics, Wayne State University, Detroit, MI, USA | [c] Division of Hematology, Wayne State University, Detroit, MI, USA | [d] Department of Pathology, Wayne State University, Detroit, MI, USA
Correspondence: [*] Address for Correspondence: Sanjay Chawla, Division of Neonatal Perinatal Medicine, Hutzel Women’s Hospital and Children’s Hospital of Michigan, Wayne State University, Detroit, MI, USA. Tel.: +1 313 745 5638; Fax: +1 313 745 5867; E-mail: SChawla@dmc.org.
Note: [1] F. Elbakoush is co-first author.
Abstract: Lead levels were measured by inductively coupled plasma mass spectrometry (ICP-MS) in umbilical cord blood samples of 150 neonates in an urban inner-city hospital. The mean (SD) gestation and birth weight of our cohort were 38.8 (1.7) weeks and 3,217 (519) grams. There were 89% African-Americans, 53% males and 79% were born via vaginal delivery. Mean (SD) maternal age was 24.5 (5.8) years. History of drug abuse and smoking was reported in 8.7% and 10.7% respectively, with only 1 mother reporting a history of high lead level in childhood. Prenatal vitamin intake was reported in 99.3%. Cord blood lead level was available in 144 patients, with lead level of <1μg/dL seen in 141 (97.9%) and>1 in 3 (2.1%) patients. No patient had cord blood lead level of >2μg/dL. High lead levels during childhood in high-risk urban population, however, suggest the need for intensive efforts for prevention of environmental exposure to lead in early childhood.
Keywords: Lead, cord blood, Detroit
DOI: 10.3233/NPM-16915131
Journal: Journal of Neonatal-Perinatal Medicine, vol. 9, no. 3, pp. 291-293, 2016
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