Affiliations: [a] Division of Cardiology, Department of Pediatrics, Stead Family Children’s Hospital, The University of Iowa, Iowa City, IA, USA
| [b] Division of Critical Care, Department of Pediatrics, Stead Family Children’s Hospital, The University of Iowa, Iowa City, IA, USA
| [c] Department of Surgery, Section of Cardiothoracic Surgery, Congenital Cardiac Surgery, Stead Family Children’s Hospital, The University of Iowa, Iowa City, IA, USA
Correspondence:
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Address for correspondence: Janelle Buysse, Division of Cardiology, Department of Pediatrics, Stead Family Children’s Hospital, The University of Iowa, 1010 BT, 200 Hawkins Drive, Iowa City, IA 52242, USA. E-mail: janelle-buysse@uiowa.edu.
Abstract: Neonatal myocardial infarction due to coronary thrombus is a rare cause of acute heart failure and is associated with high morbidity and mortality. We present a rare case of a full-term newborn who developed coronary artery thrombus treated with intracoronary recombinant tissue plasminogen activator infusion while undergoing therapeutic hypothermia. Also, we describe a unique treatment strategy to support systemic circulation sparing the patient from neonatal extracorporeal membrane oxygenation and its complications. Neonatal myocardial infarction should be suspected and ruled out in sick newborns.
