Transfusion-related hemolysis and subsequent necrotizing enterocolitis in a premature infant with Clostridium infection

Article type: Research Article

Authors: Gad, Ashraf | Ahmed, Tahmeena | Shah, Shetal

Affiliations: Division of Neonatology, Department of Pediatrics, Stony Brook University School of Medicine, NY 11794, USA | Department of Pathology, Stony Brook University School of Medicine, NY 11794, USA

Note: [] Corresponding author: Ashraf Gad, MD. Tel.: +1 631 444 7653; Fax: +1 631 444 9142; E-mail: imamgad@hotmail.com

Abstract: Packed-Red Blood Cell (PRBC) transfusion has been associated with subsequent necrotizing enterocolitis (NEC). We report a documented case of a premature infant presenting with severe intravascular hemolysis and NEC after PRBC transfusion as symptoms of underlying Clostridium perfringens infection in the bowel.

Keywords: Hemolysis, blood transfusion, NEC, clostridium

Journal: Journal of Neonatal-Perinatal Medicine, vol. 1, no. 3, pp. 197-200, 2008