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Issue title: Special Section: FLINS 2018
Guest editors: Cengiz Kahraman
Article type: Research Article
Authors: Dogu, Elifa; * | Albayrak, Y. Esraa | Tuncay, Esinb
Affiliations: [a] Industrial Engineering Department, Galatasaray University, Besiktas, Istanbul, Turkey | [b] Yedikule Chest Diseases & Thoracic Surgery Training & Research Hospital, Zeytinburnu, Istanbul, Turkey
Correspondence: [*] Corresponding author. Elif Dogu, Industrial Engineering Department, Galatasaray University, Ciragan Cad. No: 36 Ortakoy 34349 Besiktas, Istanbul, Turkey. E-mail: edogu@gsu.edu.tr.
Abstract: Tuberculosis (TB) bacteria may develop resistance to the drugs, which are used in TB treatment. Multidrug-resistant TB (MDR-TB) is a type of TB that does not respond to at least rifampicin and isoniazid, the 2 most powerful anti-TB drugs. MDR-TB requires a more compelling treatment and it is more difficult to diagnose. The experience of physician is the key factor in the success of MDR-TB diagnose. The existence of TB bacteria in the body can be observed relatively faster with a standard sputum smear however, drug-susceptibility tests require nearly 45 days. To cope with this infectious disease, it is vital to estimate the resistance in a newly diagnosed TB patient to plan the initialization of the treatment in the testing period. Herein, the purpose of this study is to build a framework and establish a mathematical model that will help decision makers (physicians) while estimating the risk of multidrug resistance when a new tuberculosis patient arrives, using intuitionistic fuzzy cognitive maps (IFCM). Intuitionistic fuzzy sets are utilized to reflect the decision makers’ hesitancy degrees in the model.
Keywords: Multidrug-resistant tuberculosis, intuitionistic fuzzy cognitive maps, medical decision support, risk factors
DOI: 10.3233/JIFS-179470
Journal: Journal of Intelligent & Fuzzy Systems, vol. 38, no. 1, pp. 1083-1095, 2020
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