Affiliations: [a] Parkinson’s Disease and Movement Disorders, University of Virginia Health System, Charlottesville, VA, USA
| [b] Neurological Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA
| [c]
Case Western Reserve University, Cleveland, OH, USA
| [d] Center for Human Genetics, University Hospitals Cleveland Medical Center, Cleveland, OH, USA
Correspondence:
[*]
Correspondence to: Alissa S. Higinbotham, MD, Parkinson’s Disease and Movement Disorders, University of Virginia Health System, 1215 Lee St. Charlottesville, VA, 22903, USA. E-mail: aue8du@uvahealth.org.
Abstract: The term “senile chorea” was previously used to describe cases of insidious onset chorea in elderly patients who lacked family history of chorea. However, many of these patients have an identifiable etiology for their chorea. In this article, we discuss a case of generalized, insidious onset chorea in an 89-year-old man and apply a systematic diagnostic approach to chorea in the elderly to arrive at a diagnosis of late-onset Huntington’s disease. He is to our knowledge the second oldest case of late-onset Huntington’s disease reported in the literature and his case lends support to the expanding phenotype of Huntington’s disease.
