Affiliations: [a]
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
| [b]
Department of Neurology, University of Florida College of Medicine, Miami, FL, USA
Correspondence:
[*]
Correspondence to: B. Christopher Morrow, MD, Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, 600N. Wolfe Street, Meyer 235, Baltimore, MD 21287, USA. E-mail: cmorrow3@jhmi.edu.
Abstract: The following commentary discusses a review by Cressot et al. entitled: ‘Psychosis in Neurodegenerative Dementias: A Systematic Comparative Review’. The authors describe the epidemiology and phenomenology of psychosis across neurodegenerative dementias. Dementia with Lewy bodies had the highest reported prevalence of psychosis at 74% followed by Alzheimer’s disease, 54% and frontotemporal degeneration, 42%. Detailed characterization of psychosis shows differences in the types of hallucinations and delusions by dementia type. These findings suggest that different types of dementia related pathology are associated with high rates of psychosis with more specific symptom profiles than previously appreciated. Understanding the differences and variety of psychotic experiences across dementia types may have diagnostic and therapeutic implications for treating hallucinations and delusions in populations suffering from neurodegenerative diseases.
