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Article type: Review Article
Authors: Tavares-Júnior, José Wagner Leonela | Ciurleo, Gabriella Cunha Vieiraa; b | Feitosa, Esther de Alencar Araripe Falcãoa | Oriá, Reinaldo B.a; b | Braga-Neto, Pedroa; c; *
Affiliations: [a] Department of Clinical Medicine, Neurology Section, Faculty of Medicine, Federal University of Ceará (UFC), Fortaleza, CE, Brazil | [b] Department of Morphology and Institute of Biomedicine, Laboratory of the Biology of Tissue Healing, Ontogeny and Nutrition, School of Medicine, Federal University of Ceara, Fortaleza, CE, Brazil | [c] Center of Health Sciences, State University of Ceará, Fortaleza, CE, Brazil
Correspondence: [*] Correspondence to: Pedro Braga-Neto, Department of Clinical Medicine, Neurology Section, Faculty of Medicine, Federal University of Ceará (UFC), Fortaleza, CE, Brazil. Tel.: +55 85 9998 5616; E-mail: pbraganeto@ufc.com.br.
Abstract: The link between long COVID-19 and brain/cognitive impairments is concerning and may foster a worrisome worldwide emergence of novel cases of neurodegenerative diseases with aging. This review aims to update the knowledge, crosstalk, and possible intersections between the Post-COVID Syndrome (PCS) and Alzheimer’s disease (AD). References included in this review were obtained from PubMed searches conducted between October 2023 and November 2023. PCS is a very heterogenous and poorly understood disease with recent evidence of a possible association with chronic diseases such as AD. However, more scientific data is required to establish the link between PCS and AD.
Keywords: Alzheimer’s disease, biomarkers, cognitive impairment, COVID-19, long COVID, post-COVID syndrome
DOI: 10.3233/JAD-231368
Journal: Journal of Alzheimer's Disease, vol. 99, no. 4, pp. 1159-1171, 2024
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