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Article type: Short Communication
Authors: Sutin, Angelina R.a; * | Aschwanden, Damarisa; b | Luchetti, Martinaa | Stephan, Yannickc | Terracciano, Antonioa
Affiliations: [a] Florida State University College of Medicine, Tallahassee, FL, USA | [b] University of Geneva, Geneva, Switzerland | [c] Euromov, University of Montpellier, Montpellier, France
Correspondence: [*] Correspondence to: Angelina R. Sutin, PhD, Florida State University College of Medicine, 1115 W. Call Street, Tallahassee, FL 32306 USA. Tel.: +1 850 645 0438; E-mail: angelina.sutin@med.fsu.edu.
Abstract: Subjective memory is useful to detect cognitive deficits not apparent on objective tests. This research evaluates whether memory rated by an interviewer predicts incident dementia. Health and Retirement Study participants without cognitive impairment at baseline whose memory was rated by the interviewer were analyzed (N = 12,749). Worse interviewer-rated memory was associated with higher risk of incident dementia over 15 years (HR = 1.40, 95% CI = 1.27–1.54). The association was evident even among participants in the top quartile of objective memory performance (HR = 1.71, 95% CI = 1.26–2.32). Interviewer-rated memory may be a low-cost supplement to neuropsychological evaluation to predict dementia risk beyond self-reports and objective cognitive testing.
Keywords: Alzheimer’s disease, early indicator, incident dementia, interviewer ratings, observer ratings, subjective memory
DOI: 10.3233/JAD-230417
Journal: Journal of Alzheimer's Disease, vol. 95, no. 1, pp. 69-74, 2023
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