Affiliations:
Pacific Health Research and Education Institute, Honolulu, HI, USA
Correspondence:
[*]
Correspondence to: Lon R. White, MD, MPH, Pacific Health Research and Education Institute, 3375 Koapaka Street, Suite I-540, Honolulu, HI 96819, USA. Tel.: +1 808 564 6421; E-mail: lon@hawaii.edu.
Abstract: While we know that brain injuries related to sport and military activities sometimes lead to cognitive impairment or early onset dementia, it is unclear if and how they might influence the development of Alzheimer’s Disease and Related Dementias (ADRD). Published analytic conclusions have been mixed. Two reports in the Journal of Alzheimer’s Disease reach the same answer: a history of brain injury appears to be a risk factor for generalized brain atrophy, which would likely increase vulnerability to the subsequent development of any variety of ADRD, or to dementia directly attributable to reduced brain mass.
