Affiliations: [a]
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA
| [b]
Indiana Alzheimer’s Disease Research Center, Indiana University School of Medicine, Indianapolis, IN, USA
Correspondence:
[*]
Correspondence to: Hugh C. Hendrie, MB, ChB, DSc, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA. Tel.: +1 317 872 8179; E-mail: hhendri@iupui.edu.
Abstract: The 1980s saw an upsurge of research in Alzheimer’s disease (AD). The necessity of standardized assessment batteries became apparent, leading to the development of standardized instruments, such as the CERAD, the CAMDEX, the CSI ’D’, and later the TOOLBOX. The advent of new biological markers has led to speculation in the research community about the necessity for these instruments. As the association of biomarkers with subsequent clinical dementia remains unclear, assessment batteries are still necessary, especially with growing evidence that prodromal symptoms of AD may not be cognitive decline but emotional or behavioral symptoms. Inclusion of ethnic minority groups is also essential.
