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Article type: Review Article
Authors: Martínez, Juan F.a; 1 | Trujillo, Catalinaa | Arévalo, Analíab | Ibáñez, Agustínc; d; e; f | Cardona, Juan F.a; *
Affiliations: [a] Instituto de Psicología, Universidad del Valle, Cali, Colombia | [b] Department of Neurology, University of São Paulo Medical School, São Paulo, Brazil | [c] Institute of Cognitive and Translational Neuroscience (INCYT), INECO Foundation, Favaloro University, Buenos Aires, Argentina | [d] National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina | [e] Center for Social and Cognitive Neuroscience (CSCN), School of Psychology, Universidad Adolfo Ibanez, Santiago, Chile | [f] Centre of Excellence in Cognition and its Disorders, Australian Research Council (ACR), Sydney, Australia
Correspondence: [*] Correspondence to: Juan F. Cardona, Universidad del Valle, Ciudad Universitaria Meléndez, Calle 13 No. 100-00, Edificio 388 Oficina 4035, Cali, Colombia. Tel.: +1 57 2 321 21 00 /Ext. 2579; E-mail: felipe.cardona@correounivalle.edu.co.
Note: [1] This work is part of Ph.D. dissertation [JF Martínez] ongoing at Universidad del Valle, Colombia.
Abstract: The visual experience of objects lies in the ability to perceive and integrate their constitutive features. Conjunctive binding (CB) is the cognitive function that integrates the features of objects as wholes. This review covers the main findings (over the last 10 years) concerning the role of CB in visual working memory (VWM) and cognitive theory, its neural correlates, as well as perspectives for future work. First, we discuss the theoretical cognitive models of CB and how these relate to other cognitive functions. We then integrate neuroimaging evidence with cognitive theory to identify the neural functional network of CB for encoding and maintenance. Also, we describe the field’s transition from experimental to clinical research, which paves the way for work in the area of VWM binding and aging. Finally, we expose the challenges faced by this field of research and analyze its role in the study of dementia and the construction of neuro-cognitive models of conjunctive binding.
Keywords: Alzheimer’s disease, conjunctive binding, mild cognitive impairment, neuropsychological assessment, working memory
DOI: 10.3233/JAD-181154
Journal: Journal of Alzheimer's Disease, vol. 69, no. 1, pp. 71-81, 2019
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